USP 800 / ASHRAE 170 Table 7-1

What it means on the job

USP 800 and ASHRAE 170 require hazardous drug (HD) compounding areas to be maintained at negative pressure relative to surrounding spaces with a minimum of 12 ACH and all air exhausted externally (no recirculation). Equal pressure means hazardous drug aerosols and vapors can escape into adjacent corridors, exposing staff and patients to carcinogenic and teratogenic compounds.

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CraftIQ explanations are original educational commentary written in trade language and verified against the cited standards. Always confirm requirements against the code edition adopted by your jurisdiction — this is training material, not a substitute for the code book or your AHJ.